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Furthermore, flow cytometry analysis demonstrated that knockdown of SLC25A39 increased the rate of cell apoptosis compared to controls, whereas overexpression of SLC25A39 exhibited the opposite effect (Fig

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2B) [39]

However, dangerous levels of methemoglobinemia only occur in patients with glucose-6-phosphate dehydrogenase (G6PDH) deficiency and, thus, this drug should not be administered to anyone with a deficiency in this enzyme